PXD056404

PXD056404 is an original dataset announced via ProteomeXchange.

Title	Human RCC Binding Protein in Prostate Cancer Cell Line DU145
Description	This study uncovers the cooperative and opposing effects of CD24 and RCC2 on tumor metastasis. CD24 regulates RCC2 through ubiquitination and degradation, and their interaction influences the β-catenin signaling pathway. RCC2 suppresses tumor metastasis by promoting cytoskeletal reorganization and degrading Vimentin, providing a deeper understanding of the molecular mechanisms underlying prostate cancer metastasis.
HostingRepository	PRIDE
AnnounceDate	2025-07-23
AnnouncementXML	Submission_2025-07-23_09:50:19.443.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Lizhong Wang
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	No PTMs are included in the dataset
Instrument	Q Exactive

Revision	Datetime	Status	ChangeLog Entry
0	2024-09-30 12:23:52	ID requested
⏵ 1	2025-07-23 09:50:19	announced

Dataset with its publication pending

submitter keyword: Human, Binding Protein, RCC, Prostate Cancer

Lizhong Wang
contact affiliation	University of Alabama at Birmingham
contact email	lwang12@uab.edu
lab head
Lizhong Wang
contact affiliation	University of Alabama at Birmingham
contact email	lwang12@uab.edu
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2025/07/PXD056404

PRIDE project URI

• PRIDE
  1. PXD056404
     1. Label: PRIDE project
     2. Name: Human RCC Binding Protein in Prostate Cancer Cell Line DU145