PXD053363 is an
original dataset announced via ProteomeXchange.
Dataset Summary
Title | Afucosylated broadly neutralizing antibodies enhance clearance of HIV-1 infected cells through NK cell mediated killing |
Description | A series of monoclonal antibodies (mAbs) against human immune deficiency virus (HIV) were prepared utilizing different variable regions targeting HIV epitopes in combination with glycoengineering to produce mAbs with low Fc fucosylation. This dataset pertains to the Fc N-glycosylation analysis of these mAbs. |
HostingRepository | PRIDE |
AnnounceDate | 2024-07-30 |
AnnouncementXML | Submission_2024-07-30_09:21:30.541.xml |
DigitalObjectIdentifier | |
ReviewLevel | Peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Unsupported dataset by repository |
PrimarySubmitter | David Falck |
SpeciesList | scientific name: Homo sapiens (Human); NCBI TaxID: 9606; |
ModificationList | complex glycosylation; iodoacetamide derivatized residue |
Instrument | impact HD |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
0 | 2024-06-24 09:50:06 | ID requested | |
⏵ 1 | 2024-07-30 09:21:30 | announced | |
Publication List
Dataset with its publication pending |
Keyword List
submitter keyword: LC-MS, monoclonal antibodies, HEK-293F cells, antibody glycosylation |
Contact List
David Falck |
contact affiliation | Center for Proteomics and Metabolomics, Leiden University Medical Center, The Netherlands |
contact email | d.falck@lumc.nl |
lab head | |
David Falck |
contact affiliation | Leiden University Medical Center |
contact email | d.falck@lumc.nl |
dataset submitter | |
Full Dataset Link List
Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2024/07/PXD053363 |
PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD053363
- Label: PRIDE project
- Name: Afucosylated broadly neutralizing antibodies enhance clearance of HIV-1 infected cells through NK cell mediated killing