PXD053336
PXD053336 is an original dataset announced via ProteomeXchange.
Dataset Summary
Title | A chemical screen identifies PRMT5 as a therapeutic vulnerability for paclitaxel-resistant triple-negative breast cancer |
Description | Through chemical probe screening, we uncovered a novel mechanism of RNA splicing in paclitaxel-resistant TNBC and identified PRMTs as therapeutic targets. |
HostingRepository | iProX |
AnnounceDate | 2024-06-22 |
AnnouncementXML | Submission_2024-06-24_00:07:12.964.xml |
DigitalObjectIdentifier | |
ReviewLevel | Peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Unsupported dataset by repository |
PrimarySubmitter | Sheyu Zhang |
SpeciesList | scientific name: Homo sapiens; NCBI TaxID: 9606; |
ModificationList | No PTMs are included in the dataset |
Instrument | Orbitrap Exploris 480 |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
---|---|---|---|
0 | 2024-06-24 00:06:12 | ID requested | |
⏵ 1 | 2024-06-24 00:07:13 | announced |
Publication List
Dataset with its publication pending |
Keyword List
submitter keyword: TNBC, paclitaxel-resistant , PRMT5, RNA-splicing, AURKB, mitosis |
Contact List
Qin Wu | |
---|---|
contact affiliation | Hangzhou Instititute of Medicine |
contact email | wuqin@ibmc.ac.cn |
lab head | |
Sheyu Zhang | |
contact affiliation | Hangzhou Instititute of Medicine |
contact email | 2020213009@tju.edu.cn |
dataset submitter |
Full Dataset Link List
iProX dataset URI |