PXD052194
PXD052194 is an original dataset announced via ProteomeXchange.
Dataset Summary
| Title | Proteomic analysis of the liver in hypophysectomy rats |
| Description | Individuals with hypopituitarism have an increased risk of developing non-alcoholic fatty liver disease (NAFLD)/non-alcoholic steatohepatitis (NASH) due to growth hormone (GH) deficiency. A rat model of hypopituitarism was established by hypophysectomy, followed by recombinant human growth hormone (rhGH) intervention. The mechanisms underlying GH deficiency-mediated NAFLD were elucidated through the application of label-free proteomics and phosphorylation proteomics. |
| HostingRepository | iProX |
| AnnounceDate | 2024-05-11 |
| AnnouncementXML | Submission_2024-05-13_18:58:10.055.xml |
| DigitalObjectIdentifier | |
| ReviewLevel | Peer-reviewed dataset |
| DatasetOrigin | Original dataset |
| RepositorySupport | Unsupported dataset by repository |
| PrimarySubmitter | Yuwen Zhang |
| SpeciesList | scientific name: Rattus rattus; NCBI TaxID: 10117; |
| ModificationList | phosphorylated residue |
| Instrument | timsTOF Pro |
Dataset History
| Revision | Datetime | Status | ChangeLog Entry |
|---|---|---|---|
| 0 | 2024-05-11 00:19:39 | ID requested | |
| ⏵ 1 | 2024-05-13 18:58:10 | announced |
Publication List
| Dataset with its publication pending |
Keyword List
| submitter keyword: Proteomic, Phosphoproteomics, hypophysectomy rats, GH deficiency, NAFLD |
Contact List
| Xuqian Fang | |
|---|---|
| contact affiliation | Ruijin Hospital, Shanghai Jiao Tong University School of Medicine |
| contact email | 251720307@qq.com |
| lab head | |
| Yuwen Zhang | |
| contact affiliation | Ruijin Hospital, Shanghai Jiao Tong University School of Medicine |
| contact email | bfzyw@163.com |
| dataset submitter | |
Full Dataset Link List
| iProX dataset URI |
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