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PXD051034

PXD051034 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleResistance target screening of ositinib-sensitive and resistant H1975 cell lines
Description(1) Extract and purify proteins from oxitinib-sensitive and resistant H1975 cell lines, screen for proteins exhibiting differences in stability using different denaturation conditions, and digest and digest them using proteases to obtain enzymatic products. (2) The enriched proteins were quantitatively analysed by liquid chromatography-mass spectrometry (LC-MS/MS) to screen for specific resistance targets.
HostingRepositoryPRIDE
AnnounceDate2024-10-22
AnnouncementXMLSubmission_2024-10-22_06:49:14.605.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterjian wang
SpeciesList scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationListiodoacetamide derivatized residue
InstrumentOrbitrap Exploris 480
Dataset History
RevisionDatetimeStatusChangeLog Entry
02024-03-27 20:21:19ID requested
12024-07-09 04:44:13announced
22024-10-22 06:49:15announced2024-10-22: Updated project metadata.
Publication List
Dataset with its publication pending
Keyword List
submitter keyword: Resistance,LC-MS,H1975,Osimertinib
Contact List
Jian wang
contact affiliationThe second hospital of dalian medical university
contact emailwj1308804060@gmail.com
lab head
jian wang
contact affiliationthe second hosptial of dalian medical university
contact emailwj1308804060@gmail.com
dataset submitter
Full Dataset Link List
Dataset FTP location
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PRIDE project URI
Repository Record List
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