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PXD050791

PXD050791 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleSubstrate and Functional Characterization of the Lysine Acetyltransferase and Deacetylase in Mycobacteria
DescriptionWe utilized the non-pathogenic M. smegmatis strain as a model and systematically investigated the dynamic proteome changes in response to the overexpressing of MsKat/MtCobB in mycobacteria. After that, the quantitative mass spectrometric method was utilized and showed that the AMP-dependent synthetase, Citrate synthase, ATP-dependent specificity component of the Clp protease, and ATP-dependent DNA/RNA helicases were identified to be the substrates of MsKat.
HostingRepositoryiProX
AnnounceDate2024-03-20
AnnouncementXMLSubmission_2024-03-19_23:35:45.150.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterJunyu Xu
SpeciesList scientific name: Mycolicibacterium smegmatis MC2 51; NCBI TaxID: 1445611;
ModificationListacetylated residue
InstrumentQ Exactive HF-X
Dataset History
RevisionDatetimeStatusChangeLog Entry
02024-03-19 23:35:00ID requested
12024-03-19 23:35:45announced
Publication List
Dataset with its publication pending
Keyword List
submitter keyword: Mycobacteria, Acetylome, Acetyltransferase, Deacetylase
Contact List
Minjia Tan
contact affiliationChinese Academy of Sciences Shanghai Institute of Materia Medica
contact emailmjtan@simm.ac.cn
lab head
Junyu Xu
contact affiliationChinese Academy of Sciences Shanghai Institute of Materia Medica
contact emailXJY89089@163.com
dataset submitter
Full Dataset Link List
iProX dataset URI