PXD049301 is an
original dataset announced via ProteomeXchange.
Dataset Summary
Title | Helical superstructures between amyloid and collagen VI in heart derived fibrils from a patient with Light Chain Amyloidosis |
Description | We investigated the N- and C-terminome of the LCs proteoforms in fibrils extracted from the hearts of a patient affected by AL amyloidosis, using a proteomic approach based on N- and C-terminal residues derivatization, followed by mapping of fragmentation sites on the structures of fibrillar LCs |
HostingRepository | PRIDE |
AnnounceDate | 2024-10-22 |
AnnouncementXML | Submission_2024-10-22_06:48:12.058.xml |
DigitalObjectIdentifier | |
ReviewLevel | Peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Unsupported dataset by repository |
PrimarySubmitter | Giulia Mazzini |
SpeciesList | scientific name: Homo sapiens (Human); NCBI TaxID: 9606; |
ModificationList | amidated residue; dimethylated residue; iodoacetamide derivatized residue |
Instrument | Q Exactive |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
0 | 2024-02-09 06:39:27 | ID requested | |
1 | 2024-07-02 09:22:48 | announced | |
⏵ 2 | 2024-10-22 06:48:12 | announced | 2024-10-22: Updated project metadata. |
Publication List
Dataset with its publication pending |
Keyword List
submitter keyword: amyloid fibrils |
fragmentation sites |
immunoglobulin light chains |
Contact List
Giovanni Palladini |
contact affiliation | Fondazione IRCCS Policlinico San Matteo |
contact email | g.palladini@smatteo.pv.it |
lab head | |
Giulia Mazzini |
contact affiliation | Fondazione IRCCS Policlinico San Matteo |
contact email | g.mazzini@smatteo.pv.it |
dataset submitter | |
Full Dataset Link List
Dataset FTP location
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PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD049301
- Label: PRIDE project
- Name: Helical superstructures between amyloid and collagen VI in heart derived fibrils from a patient with Light Chain Amyloidosis