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PXD047723

PXD047723 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitlePlasma-derived extracellular vesicles from patients with liver cirrhosis and hepatocellular carcinoma
DescriptionQuantitative label-free proteomic analysis of extracellular vesicles. A pool of isolated proteins from extracellular vesicles (EVs) was performed for each sample group, namely healthy participants (HP), liver cirrhosis (LC), and hepatocellular carcinoma (HCC), split into three biological replicates. Then, samples were digested with trypsin, and the peptides were subjected to Nano LC-MS/MS Analysis and Mass Spectrometry. Nine raw MS files were analyzed and searched against the human protein database based on the species of the samples using Maxquant. The parameters were set as follows: the protein modifications were carbamidomethylation (C) (fixed), oxidation (M) (variable); the enzyme specificity was set to trypsin; the maximum missed cleavage was set to 2; the precursor ion mass tolerance was set to 10 ppm, and MS/MS tolerance was 0.5 Da.
HostingRepositoryjPOST
AnnounceDate2024-07-09
AnnouncementXMLSubmission_2024-07-09_12:57:03.010.xml
DigitalObjectIdentifier
ReviewLevelNon peer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterVerónica Rocío Vásquez Garzón
SpeciesList scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationListS-carboxamidomethyl-L-cysteine; L-methionine sulfoxide
InstrumentQ Exactive
Dataset History
RevisionDatetimeStatusChangeLog Entry
02023-12-11 10:26:38ID requested
12024-07-09 12:57:03announced
Publication List
Dataset with its publication pending
Keyword List
submitter keyword: extracelular vesicles, liver cirrhosis, hepatocellular carcinoma
Contact List
PhD. Verónica Rocío Vásquez-Garzón
lab head
Verónica Rocío Vásquez Garzón
contact affiliationFacultad de medicina y cirugía, Universidad Autónoma Benito Juárez de Oaxaca
dataset submitter
Full Dataset Link List
jPOST dataset URI
Dataset FTP location
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