PXD046759

PXD046759 is an original dataset announced via ProteomeXchange.

Title	Role of the Yersinia pestis Phospholipase D (Ymt) in the Initial Aggregation Step of Biofilm Formation in the Flea
Description	Transmission of Yersinia pestis by fleas depends on the formation of condensed bacterial aggregates embedded within a gel-like matrix that localize to the proventricular valve in the flea foregut and interfere with normal blood feeding.The matrix of the bacterial aggregates is complex,containing large amounts of protein and lipid (particularly cholesterol) derived from the flea's blood meal. The goal of this study was to biochemically characterize the EPS of the Y. pestis aggregates that form after infection and to identify factors required for this initial stage of biofilm formation.
HostingRepository	PRIDE
AnnounceDate	2024-10-22
AnnouncementXML	Submission_2024-10-22_06:38:17.105.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Yixiang Zhang
SpeciesList	scientific name: Mus musculus (Mouse); NCBI TaxID: 10090; scientific name: Xenopsylla cheopis; NCBI TaxID: 163159; scientific name: Yersinia pestis CO92; NCBI TaxID: 214092;
ModificationList	monohydroxylated residue; iodoacetamide derivatized residue
Instrument	Orbitrap Fusion Lumos

Revision	Datetime	Status	ChangeLog Entry
0	2023-11-07 14:39:32	ID requested
1	2024-05-06 15:16:34	announced
⏵ 2	2024-10-22 06:38:17	announced	2024-10-22: Updated project metadata.

Dataset with its publication pending

submitter keyword: flea, biofilm,Yersinia pestis

B Joseph Hinnebusch
contact affiliation	Laboratory of Bacteriology, Rocky Mountain Laboratories, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Hamilton, MT 59840, USA.
contact email	jhinnebusch51@gmail.com
lab head
Yixiang Zhang
contact affiliation	RML/NIAID/NIH
contact email	alexzhangyx@gmail.com
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2024/05/PXD046759

PRIDE project URI

• PRIDE
  1. PXD046759
     1. Label: PRIDE project
     2. Name: Role of the Yersinia pestis Phospholipase D (Ymt) in the Initial Aggregation Step of Biofilm Formation in the Flea