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PXD046748

PXD046748 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleHistone modification profile of Pristionchus pacificus
DescriptionPristionchus pacificus has emerged as a valuable model system for comparative and evolutionary-developmental biology (evo-devo) studies alongside the classic model nematode C. elegans. Previous studies have identified a lack of conservation of genetic networks underlying conserved traits, referred to as developmental systems drift. However, the conservation – or lack thereof – of epigenetic pathways which regulate development have not been investigated. In the manuscript associated with this study, we present an “epigenetic toolkit” for P. pacificus and C. elegans to compare and contrast epigenetic pathways. Assembly of this toolkit was done by identifying orthologous genes, including the “writers” and “erasers” of histone modifications. To complement this evolutionary approach, here we produce a data set of the suite of histone modifications present in P. pacificus.
HostingRepositoryPRIDE
AnnounceDate2024-10-22
AnnouncementXMLSubmission_2024-10-22_06:33:23.384.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterMirita Franz-Wachtel
SpeciesList scientific name: Nematoda; NCBI TaxID: NCBITaxon:6231; scientific name: Pristionchus pacificus; NCBI TaxID: 54126;
ModificationListmonomethylated residue; ubiquitinylated lysine; crotonylated L-lysine; trimethylated residue; phosphorylated residue; acetylated residue; dimethylated residue; N6-butanoyl-L-lysine; iodoacetamide derivatized residue; N6-((3R)-3-hydroxybutanoyl)-L-lysine; O-(N-acetylamino)hexosyl-L-serine; O-(N-acetylamino)hexosyl-L-threonine; N6-propanoyl-L-lysine
InstrumentQ Exactive HF-X
Dataset History
RevisionDatetimeStatusChangeLog Entry
02023-11-07 07:34:44ID requested
12024-03-14 02:23:13announced
22024-10-22 06:33:23announced2024-10-22: Updated project metadata.
Publication List
Dataset with its publication pending
Keyword List
submitter keyword: epigenetics, P. pacificus,histone modifications, nematodes
Contact List
Michael S. Werner
contact affiliationUniversity of Utah, School of Biological Sciences Salt Lake City, Utah, U.S.A.
contact emailmichael.werner@utah.edu
lab head
Mirita Franz-Wachtel
contact affiliationProteome Center Tuebingen
contact emailmirita.franz@uni-tuebingen.de
dataset submitter
Full Dataset Link List
Dataset FTP location
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PRIDE project URI
Repository Record List
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