PXD045519 is an
original dataset announced via ProteomeXchange.
Dataset Summary
Title | Proteomic biomarkers in seminal plasma as predictors of reproductive potential in azoospermic men |
Description | This prospective study aimed to discover biomarkers in seminal plasma that could be employed for a non-invasive differential diagnosis of OA/NOA in order to rationalize surgery recommendations and improve success rates. Using label-free LC-MS/MS, we compared the proteomes of seminal plasma samples from fertile men (HC, n=8) and infertile men diagnosed with 1) OA (n=7), 2) NOA with successful sperm retrieval (mixed atrophy, n=8), and 3) NOA without sperm retrieval (Sertoli cell-only phenotype, n=7). |
HostingRepository | PRIDE |
AnnounceDate | 2024-10-22 |
AnnouncementXML | Submission_2024-10-22_06:34:15.453.xml |
DigitalObjectIdentifier | |
ReviewLevel | Peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Unsupported dataset by repository |
PrimarySubmitter | Laura Dagley |
SpeciesList | scientific name: Homo sapiens (Human); NCBI TaxID: 9606; |
ModificationList | monohydroxylated residue; iodoacetamide derivatized residue |
Instrument | impact II |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
0 | 2023-09-20 05:45:32 | ID requested | |
1 | 2024-03-20 17:53:05 | announced | |
⏵ 2 | 2024-10-22 06:34:15 | announced | 2024-10-22: Updated project metadata. |
Publication List
Dataset with its publication pending |
Keyword List
submitter keyword: Azoospermia, seminal plasma, Diagnosis, Proteomics, Testicular failure, biomarker |
Contact List
Daniela Fietz |
contact affiliation | Institute for Veterinary Anatomy, Justus Liebig University Giessen Frankfurter Strasse 98, 35392 Giessen, Germany |
contact email | Daniela.Fietz@vetmed.uni-giessen.de |
lab head | |
Laura Dagley |
contact affiliation | WEHI |
contact email | dagley.l@wehi.edu.au |
dataset submitter | |
Full Dataset Link List
Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2024/03/PXD045519 |
PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD045519
- Label: PRIDE project
- Name: Proteomic biomarkers in seminal plasma as predictors of reproductive potential in azoospermic men