PXD044950 is an
original dataset announced via ProteomeXchange.
Dataset Summary
Title | Structural basis for the toxicity of Legionella pneumophila effector SidH |
Description | Legionella pneumophila (LP) secretes more than 300 effectors into the host cytosol to facilitate intracellular replication. One of these effectors, SidH does not have sequence similarityto proteins of known function and is toxic when overexpressed in host cells. In order to understand the mechanism and function, it is important to know what host factors, SidH interacts with in human cells. Using quantitative proteomics, we uncovered multiple host proteins as potential targets of SidH. |
HostingRepository | PRIDE |
AnnounceDate | 2023-10-02 |
AnnouncementXML | Submission_2023-10-02_06:39:25.031.xml |
DigitalObjectIdentifier | |
ReviewLevel | Peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Unsupported dataset by repository |
PrimarySubmitter | rahulsharma |
SpeciesList | scientific name: Homo sapiens (Human); NCBI TaxID: 9606; |
ModificationList | No PTMs are included in the dataset |
Instrument | Orbitrap Fusion Lumos |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
0 | 2023-08-30 01:10:59 | ID requested | |
⏵ 1 | 2023-10-02 06:39:25 | announced | |
Publication List
Dataset with its publication pending |
Keyword List
submitter keyword: SidH, LC-MS, interactors,Legionella pneumophila |
Contact List
SagarBhogaraju |
contact affiliation | EMBL Grenoble |
contact email | bhogaraju@embl.fr |
lab head | |
rahulsharma |
contact affiliation | post-doc |
contact email | rsharma@embl.fr |
dataset submitter | |
Full Dataset Link List
Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2023/10/PXD044950 |
PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD044950
- Label: PRIDE project
- Name: Structural basis for the toxicity of Legionella pneumophila effector SidH