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PXD044287

PXD044287 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleTargeting IRE1α reprograms the tumor microenvironment and enhances anti-tumor immunity in prostate cancer
DescriptionUnfolded protein response (UPR) is a central stress response pathway in normal cells that is hijacked by tumor cells for their survival. However, how activation of UPR in cancer cells shapes the tumor microenvironment (TME) remain largely unexplored. Here, we investigated the role of IRE1α-XBP1s on modulation of TME dynamics in prostate cancer (PCa).
HostingRepositoryPRIDE
AnnounceDate2024-08-28
AnnouncementXMLSubmission_2024-08-28_08:11:21.876.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterFrank Stein
SpeciesList scientific name: Mus musculus (Mouse); NCBI TaxID: 10090;
ModificationListNo PTMs are included in the dataset
InstrumentOrbitrap Fusion Lumos
Dataset History
RevisionDatetimeStatusChangeLog Entry
02023-08-02 01:09:21ID requested
12024-08-28 08:11:22announced
Publication List
Dataset with its publication pending
Keyword List
submitter keyword: IRE1 prostate cancer tumor microenvironment
Contact List
Fahri Saatcioglu
contact affiliationUniversity of Oslo
contact emailfahri.saatcioglu@ibv.uio.no
lab head
Frank Stein
contact affiliationEMBL
contact emailfrank.stein@embl.de
dataset submitter
Full Dataset Link List
Dataset FTP location
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PRIDE project URI
Repository Record List
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