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PXD044163

PXD044163 is an original dataset announced via ProteomeXchange.

Dataset Summary

Title	GlycoTCFM: glycoproteomics based on two complementary fragmentation methods reveals distinctive O-glycosylation in human semen
Description	Human semen, consisting of spermatozoa and seminal plasma, represents a special clinical sample type in human body fluid. Protein glycosylation in semen plays key roles in spermatogenesis, maturation, capacitation, sperm–egg recognition, motility of sperm and fertilization. In this study, we profiled the most comprehensive O-glycoproteome map of human semen using our recently presented glycoproteomics based on two complementary fragmentation methods (GlycoTCFM). We showed that semen contains a lot of novel and distinctive O-glycoproteins, which are mostly located in extracellular region and membrane, enriched in the biological processes of cell adhesion and angiogenesis, and mainly involved in multiple biological functions including extracellular matrix structural constituent and binding.
HostingRepository	iProX
AnnounceDate	2023-07-28
AnnouncementXML	Submission_2023-07-27_23:08:16.275.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Yong Zhang
SpeciesList	scientific name: Homo sapiens; NCBI TaxID: 9606;
ModificationList	complex glycosylation
Instrument	Orbitrap Fusion Lumos

Dataset History

Revision	Datetime	Status	ChangeLog Entry
0	2023-07-27 23:08:02	ID requested
⏵ 1	2023-07-27 23:08:16	announced

Publication List

Dataset with its publication pending

Keyword List

submitter keyword: Semen

Contact List

Yong Zhang
contact affiliation	West China Hospital, Sichuan University
contact email	nankai1989@foxmail.com
lab head
Yong Zhang
contact affiliation	West China Hospital, Sichuan University
contact email	nankai1989@foxmail.com
dataset submitter

Full Dataset Link List

iProX dataset URI