PXD040579

PXD040579 is an original dataset announced via ProteomeXchange.

Title	Evidence of a role for CutRS and actinorhodin in the secretion stress response in Streptomyces coelicolor M145
Description	This work was carried out to elucidate the proteins that are regulated by the two-component system CutRS in Streptomyces coelicolor M145 and how this response changes in the presence of glucose. A comparison of the whole cell proteomes of Streptomyces coelicolor M145 WT and Streptomyces coelicolor M145 ∆cutRS on both DNA (no glucose) and DNAD (with glucose) was made.
HostingRepository	PRIDE
AnnounceDate	2024-10-22
AnnouncementXML	Submission_2024-10-22_05:48:28.134.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Gerhard Saalbach
SpeciesList	scientific name: Streptomyces coelicolor A3(2); NCBI TaxID: 100226;
ModificationList	TMT6plex-126 reporter+balance reagent acylated residue; monohydroxylated residue; iodoacetamide derivatized residue
Instrument	Orbitrap Eclipse

Revision	Datetime	Status	ChangeLog Entry
0	2023-03-03 07:56:08	ID requested
1	2023-06-16 10:16:46	announced
⏵ 2	2024-10-22 05:48:28	announced	2024-10-22: Updated project metadata.

Dataset with its publication pending

submitter keyword: antibiotics,Streptomyces, two-component system, protein secretion, actinorhodin, secretion stress

Matt Hutchings
contact affiliation	Department Molecular Microbiology John Innes Centre Norwich, UK
contact email	matt.hutchings@jic.ac.uk
lab head
Gerhard Saalbach
contact affiliation	Biological Chemistry
contact email	gerhard.saalbach@jic.ac.uk
dataset submitter

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PRIDE project URI

• PRIDE
  1. PXD040579
     1. Label: PRIDE project
     2. Name: Evidence of a role for CutRS and actinorhodin in the secretion stress response in Streptomyces coelicolor M145