PXD040128
PXD040128 is an original dataset announced via ProteomeXchange.
Dataset Summary
| Title | A contractile injection system is required for developmentally regulated cell death in Streptomyces coelicolor |
| Description | Diverse bacterial species produce extracellular contractile injection systems (eCISs). Although closely related to contractile phage tails, eCISs can inject toxic proteins into eukaryotic cells. Thus, these systems are commonly viewed as cytotoxic defense mechanisms that are not central to other aspects of bacterial biology. Here, we provide evidence that eCISs appear to participate in the complex developmental process of the bacterium Streptomyces coelicolor. In particular, we show that S. coelicolor produces eCIS particles during its normal growth cycle, and that strains lacking functional eCIS particles exhibit pronounced alterations in their developmental program. |
| HostingRepository | MassIVE |
| AnnounceDate | 2023-02-20 |
| AnnouncementXML | Submission_2023-02-20_15:20:48.423.xml |
| DigitalObjectIdentifier | |
| ReviewLevel | Non peer-reviewed dataset |
| DatasetOrigin | Original dataset |
| RepositorySupport | Unsupported dataset by repository |
| PrimarySubmitter | Maria Vladimirov |
| SpeciesList | scientific name: Streptomyces coelicolor A3(2); NCBI TaxID: 100226; |
| ModificationList | No PTMs are included in the dataset |
| Instrument | Q Exactive |
Dataset History
| Revision | Datetime | Status | ChangeLog Entry |
|---|---|---|---|
| 0 | 2023-02-15 14:03:26 | ID requested | |
| ⏵ 1 | 2023-02-20 15:20:48 | announced |
Publication List
| no publication |
Keyword List
| submitter keyword: Streptomyces, phage tail, contractile injection system |
Contact List
| Alan Davidson | |
|---|---|
| contact affiliation | University |
| contact email | alan.davidson@utoronto.ca |
| lab head | |
| Maria Vladimirov | |
| contact affiliation | University of Toronto |
| contact email | mariavld118@gmail.com |
| dataset submitter | |
Full Dataset Link List
| MassIVE dataset URI |
| Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://massive.ucsd.edu/MSV000091288/ |
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