PXD039915 is an
original dataset announced via ProteomeXchange.
Dataset Summary
Title | The direct effect of mycophenolate mofetil on podocytes in nephrotoxic serum nephritis |
Description | The goal of our study was to characterize glomerulus and particularly podocyte biology during MMF treatment in an immune-triggered proteinuric glomerulopathy. Therefore, nephrotoxic serum nephritis was induced in three-week old wild-type mice. On day 3, half of the mice were treated with MMF (100 mg/kgBW/d p.o.) (NTS+MMF) for one week, the other half of animals with vehicle (NTS+veh). A further group without induction and treatment served as controls (C). On day 10, we performed proteomic analysis of glomeruli. |
HostingRepository | PRIDE |
AnnounceDate | 2023-08-30 |
AnnouncementXML | Submission_2023-08-30_01:00:19.749.xml |
DigitalObjectIdentifier | |
ReviewLevel | Peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Unsupported dataset by repository |
PrimarySubmitter | PreranaWagle |
SpeciesList | scientific name: Mus musculus (Mouse); NCBI TaxID: 10090; |
ModificationList | iodoacetamide derivatized residue |
Instrument | Q Exactive Plus |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
0 | 2023-02-07 13:41:11 | ID requested | |
⏵ 1 | 2023-08-30 01:00:20 | announced | |
Publication List
Dataset with its publication pending |
Keyword List
submitter keyword: super-resolution imaging, intracellular Ca2+ imaging, actin cytoskeleton, multiphoton microscopy, renal epithelial cell,immune complex-mediated glomerulopathy, mycophenolic acid, glomerular filtration barrier |
Contact List
AgnesHackl |
contact affiliation | Pediatric Nephrology, Department of Pediatrics Faculty of Medicine and University Hospital Cologne, Kerpener Street 62, 50937, Cologne, Germany |
contact email | agnes.hackl@uk-koeln.de |
lab head | |
PreranaWagle |
contact affiliation | CECAD Research Center |
contact email | proteomics-facility@uni-koeln.de |
dataset submitter | |
Full Dataset Link List
Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2023/08/PXD039915 |
PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD039915
- Label: PRIDE project
- Name: The direct effect of mycophenolate mofetil on podocytes in nephrotoxic serum nephritis