PXD039339

PXD039339 is an original dataset announced via ProteomeXchange.

Title	Tissue expression of N-terminal proteoforms.
Description	To evaluate the expression of N-terminal proteoforms (protein isoforms with different N-terminus expressed from the same gene) in healthy human tissues, we re-analyzed public proteomics data of the draft map of the human proteome developed by the Pandey group (PRIDE project PXD000561). Using ionbot search engine and a custom-build protein sequence database (composed of UniProt and Ribo-seq derived proteoforms) we confirmed that N-terminal proteoforms are not only expressed in histologically healthy human tissues, but also display tissue specificity.
HostingRepository	PRIDE
AnnounceDate	2023-06-12
AnnouncementXML	Submission_2023-06-12_10:01:45.606.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	DariaFijalkowska
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	acetylated residue; monohydroxylated residue; iodoacetamide derivatized residue
Instrument	LTQ Orbitrap Velos; LTQ Orbitrap Elite

Revision	Datetime	Status	ChangeLog Entry
0	2023-01-09 07:37:45	ID requested
⏵ 1	2023-06-12 10:01:46	announced

Dataset with its publication pending

submitter keyword: proteoforms, healthy tissue,human

Prof. Dr. KrisGevaert
contact affiliation	Principal Investigator and Associate Director – VIB-UGent Center for Medical Biotechnology, Belgium Head of Department – UGent Department of Biomolecular Medicine, Belgium
contact email	kris.gevaert@vib-ugent.be
lab head
DariaFijalkowska
contact affiliation	VIB-UGent Center for Medical Biotechnology
contact email	daria.fijalkowska@vib-ugent.be
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2023/06/PXD039339

PRIDE project URI

• PRIDE
  1. PXD039339
     1. Label: PRIDE project
     2. Name: Tissue expression of N-terminal proteoforms.