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PXD039260

PXD039260 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleBispecific antigen therapy plasma proteome
DescriptionBispecific-antibody therapy (BAT), the next strategy of immunotherapy for tumor patients, has showed the enhanced antitumor benefits than the monotherapy. Yet, few effective biomarkers were developed to monitor the response. Here, we investigated the first BAT longitudinal plasma proteome profiling including 86 longitudinal samples from 22 tumor patients who received anti-PD1 and anti-CTLA4 BAT therapy and 24 healthy control samples, which might be beneficial to explore the biomarker for BAT.
HostingRepositoryiProX
AnnounceDate2024-02-20
AnnouncementXMLSubmission_2024-08-05_20:14:43.598.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterJiacheng Lyu
SpeciesList scientific name: Homo sapiens; NCBI TaxID: 9606;
ModificationListNo PTMs are included in the dataset
InstrumentQ Exactive HF-X
Dataset History
RevisionDatetimeStatusChangeLog Entry
02023-01-04 20:20:20ID requested
12024-08-05 20:14:44announced
Publication List
Dataset with its publication pending
Keyword List
submitter keyword: immunotherapy, bispecific antigen therapy, plasma proteome, biomarker
Contact List
Chen Ding
contact affiliationFudan University
contact emailcrickding@163.com
lab head
Jiacheng Lyu
contact affiliationFudan University
contact emailjydcz1028@163.com
dataset submitter
Full Dataset Link List
iProX dataset URI