PXD037844 is an
original dataset announced via ProteomeXchange.
Dataset Summary
Title | Human Beta Defensin-2-mediated protection of human skin barrier in vitro; a mechanistic evaluation |
Description | I this project we performed global proteomic and secretomic analyses, following HBD2 stimulation, with or without V8-mediated damage, demonstrating minimal impact of the peptide alone on undamaged cells and showing that HBD2 did not induce expression of known antiproteases, but rather may function by modulating expression of extracellular matrix proteins. |
HostingRepository | PRIDE |
AnnounceDate | 2023-11-14 |
AnnouncementXML | Submission_2023-11-14_08:58:35.178.xml |
DigitalObjectIdentifier | |
ReviewLevel | Peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Unsupported dataset by repository |
PrimarySubmitter | Jimi Wills |
SpeciesList | scientific name: Homo sapiens (Human); NCBI TaxID: 9606; |
ModificationList | No PTMs are included in the dataset |
Instrument | Q Exactive Plus |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
0 | 2022-10-31 09:04:54 | ID requested | |
1 | 2023-02-09 07:03:37 | announced | |
⏵ 2 | 2023-11-14 08:58:35 | announced | 2023-11-14: Updated project metadata. |
Publication List
Dataset with its publication pending |
Keyword List
submitter keyword: Defensins |
Antimicrobial Host Defence Peptide |
Atopic Dermatitis |
Staphylococcus aureus |
Contact List
Donald J. Davidson |
contact affiliation | University of Edinburgh Centre for Inflammation Research, Queen’s Medical Research Institute, University of Edinburgh, Scotland, UK |
contact email | Donald.Davidson@ed.ac.uk |
lab head | |
Jimi Wills |
contact affiliation | Firefinch Software Ltd formerly Univeristy of Edinburgh |
contact email | jimi@firefinch.io |
dataset submitter | |
Full Dataset Link List
Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2023/02/PXD037844 |
PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD037844
- Label: PRIDE project
- Name: Human Beta Defensin-2-mediated protection of human skin barrier in vitro; a mechanistic evaluation