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PXD036849

PXD036849 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleComprehensive characterization of the Hsp70 interactome reveals novel client proteins and interactions mediated by post-translational modifications
DescriptionHsp70 interactions are critical for cellular viability and the response to stress. Previous attempts to characterize Hsp70 interactions have been limited by their transient nature and inability of current technologies to distinguish direct vs bridged interactions. We report the novel use of cross-linking mass spectrometry (XL-MS) to comprehensively characterize the budding yeast Hsp70 protein interactome.
HostingRepositoryMassIVE
AnnounceDate2022-09-19
AnnouncementXMLSubmission_2022-09-19_16:38:29.291.xml
DigitalObjectIdentifier
ReviewLevelNon peer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportSupported dataset by repository
PrimarySubmitterLuca Fornelli
SpeciesList scientific name: Saccharomyces cerevisiae; common name: baker's yeast; NCBI TaxID: 4932;
ModificationListAcetyl; Methyl; Phospho
InstrumentOrbitrap Fusion Lumos
Dataset History
RevisionDatetimeStatusChangeLog Entry
02022-09-19 15:09:22ID requested
12022-09-19 16:38:29announced
Publication List
no publication
Keyword List
submitter keyword: Hsp70, Ssa1, chaperone, crosslinking, mass spectrometry, post-translational modifications, interactions, proteomics
Contact List
Andrew W Truman
contact affiliationUniversity of North Carolina at Charlotte
contact emailA.Truman@uncc.edu
lab head
Luca Fornelli
contact affiliationUniversity of Oklahoma
contact emailluca.fornelli@ou.edu
dataset submitter
Full Dataset Link List
MassIVE dataset URI
Dataset FTP location
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