PXD036161 is an
original dataset announced via ProteomeXchange.
Dataset Summary
Title | High-throughput proteomics of the 26 medically most important elapids and vipers from sub-Saharan Africa |
Description | Venomous snakes are important parts of the ecosystem, and their behavior and evolution have been shaped by their surrounding environments over the eons. This is reflected in their venoms, which are typically highly adapted for their biological niche, including their diet and defense mechanisms for deterring predators. Sub-Saharan Africa is rich in venomous snake species, of which many are dangerous to humans due to the high toxicity of their venoms and their ability to effectively deliver large amounts of venom into their victims via their bite. In this study, the venoms of 26 of sub-Saharan Africa’s medically most relevant elapid and viper species were subjected to parallelized toxicovenomics analysis. The analysis included venom proteomics and enables a robust comparison of venom profiles between species. Moreover, two new venom proteomes (N. anchietae and E. leucogaster) are presented here for the first time. |
HostingRepository | PRIDE |
AnnounceDate | 2022-10-17 |
AnnouncementXML | Submission_2022-10-17_06:10:37.324.xml |
DigitalObjectIdentifier | |
ReviewLevel | Peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Unsupported dataset by repository |
PrimarySubmitter | CarolO'Brien |
SpeciesList | scientific name: Cerastes cerastes; NCBI TaxID: 8697; scientific name: Hemachatus haemachatus; NCBI TaxID: 8626; scientific name: Dendroaspis viridis; NCBI TaxID: 8621; scientific name: Dendroaspis angusticeps (Eastern green mamba) (Naja angusticeps); NCBI TaxID: 8618; scientific name: Naja nivea; NCBI TaxID: 8655; scientific name: Dendroaspis polylepis; NCBI TaxID: 8624; scientific name: Naja katiensis; NCBI TaxID: 409859; scientific name: Naja haje; NCBI TaxID: 8639; scientific name: Echis pyramidum; NCBI TaxID: 8700; scientific name: Naja senegalensis; NCBI TaxID: 862238; scientific name: Naja nigricollis; NCBI TaxID: 8654; scientific name: Naja melanoleuca; NCBI TaxID: 8643; scientific name: Naja ashei; NCBI TaxID: 696811; scientific name: Naja annulifera; NCBI TaxID: 96794; scientific name: Bitis arietans; NCBI TaxID: 8692; scientific name: Bitis nasicornis; NCBI TaxID: 8695; scientific name: Naja anchietae; NCBI TaxID: 263737; scientific name: Naja pallida; NCBI TaxID: 8658; scientific name: Naja nigricincta; NCBI TaxID: 409860; scientific name: Bitis rhinoceros; NCBI TaxID: 715877; scientific name: Echis ocellatus; NCBI TaxID: 99586; scientific name: Bitis gabonica; NCBI TaxID: 8694; scientific name: Naja nubiae; NCBI TaxID: 186441; scientific name: Echis leucogaster; NCBI TaxID: 504457; scientific name: Naja mossambica; NCBI TaxID: 8644; scientific name: Dendroaspis jamesoni; NCBI TaxID: 8623; |
ModificationList | acetylated residue; monohydroxylated residue; deamidated residue; iodoacetamide derivatized residue |
Instrument | Q Exactive HF |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
0 | 2022-08-19 00:35:27 | ID requested | |
⏵ 1 | 2022-10-17 06:10:37 | announced | |
Publication List
Dataset with its publication pending |
Keyword List
submitter keyword: snakebite envenoming,snake venom, venomics |
Contact List
Andreas H.Laustsen |
contact affiliation | Technical University of Denmark |
contact email | ahola@bio.dtu.dk |
lab head | |
CarolO'Brien |
contact affiliation | Technical University of Denmark |
contact email | cmaob@dtu.dk |
dataset submitter | |
Full Dataset Link List
Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2022/10/PXD036161 |
PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD036161
- Label: PRIDE project
- Name: High-throughput proteomics of the 26 medically most important elapids and vipers from sub-Saharan Africa