PXD035618

PXD035618 is an original dataset announced via ProteomeXchange.

Title	Insights into the digestive gland of Mytilus coruscus under heat stress using TMT-based proteomics
Description	A healthy existence relationship between mussels and environment relies on suitable PH, adequate oxygen and suitable temperature. Besides ocean acidification, ocean warming has been shown to cause mussel dead, a phenomenon responsible for extensive mussel dead around the word. How heat stress impacts mussel alive is poorly understood. We founded that. The superoxide dismutase (SOD) activity of two treatment groups were significantly higher than that of control group, and the activity of acid phosphatase (ACP) was significantly higher in two treatment groups than control group. The lactate dehydrogenase (LDH) activity of 26 ℃ treatment group was significantly higher than that of control group, and the LDH activity of 33 ℃ treatment group was significantly lower than that of control group. Cellular content of lysozyme (LZM) was significantly higher in two treatment groups than control group. In this study, we applied TMT quantification to investigate how Mytilus coruscus responds to heat stress (26 ℃, 33 ℃). We identified 1652 to 1878 differentially expressed proteins (DEPs) from these heat conditions, among which 897 were commonly regulated by all the two temperature and were significantly enriched in nutrients digestion and absorption (e. g. fat digestion and absorption). Furthermore, proteins associated with nutrients metabolism, signaling pathways (p53 signaling pathway and MAPK signaling pathway)and energy metabolism (e. g. TCA cycle) were impacted, suggesting that the ability of basic metabolism of Mytilus coruscus may be altered by heat stress.
HostingRepository	PRIDE
AnnounceDate	2023-05-30
AnnouncementXML	Submission_2023-05-30_01:04:19.765.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	乐钟许
SpeciesList	scientific name: Mytilus coruscus; NCBI TaxID: 42192;
ModificationList	TMT6plex-126 reporter+balance reagent acylated residue
Instrument	Q Exactive

Revision	Datetime	Status	ChangeLog Entry
0	2022-07-29 06:55:45	ID requested
⏵ 1	2023-05-30 01:04:20	announced

Dataset with its publication pending

submitter keyword: heat stress,Mytlius coruscus,TMT

Insights into the digestive gland of Mytilus coruscus under heat stress using TMT-basedproteomics
contact affiliation	Zhejiang Ocean University
contact email	3454606890@qq.com
lab head
乐钟许
contact affiliation	19883838836
contact email	3454606890@qq.com
dataset submitter

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PRIDE project URI

• PRIDE
  1. PXD035618
     1. Label: PRIDE project
     2. Name: Insights into the digestive gland of Mytilus coruscus under heat stress using TMT-based proteomics