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PXD034801

PXD034801 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleLack of TRPV1 Channel Modulates Mouse Gene Expression and Liver Proteome with Glucose Metabolism Changes
DescriptionTo investigate the role of the transient receptor potential channel vanilloid type 1 (TRPV1) channel in hepatic glucose metabolism, we performed proteomics analysis of the liver of C57Bl/6J (WT) and Trpv1 KO mice (n = 4 per group). Liver from Trpv1 KO mice showed significant proteomics changes consistent with enhanced glycogenolysis, as well as increased gluconeogenesis and inflammatory features.
HostingRepositoryMassIVE
AnnounceDate2022-06-21
AnnouncementXMLSubmission_2022-06-21_13:37:05.173.xml
DigitalObjectIdentifier
ReviewLevelNon peer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterJose Thalles Lacerda
SpeciesList scientific name: Mus musculus; common name: house mouse; NCBI TaxID: 10090;
ModificationListOxidation; Carboxymethyl; Acetyl
InstrumentmaXis
Dataset History
RevisionDatetimeStatusChangeLog Entry
02022-06-21 13:20:22ID requested
12022-06-21 13:37:05announced
Publication List
no publication
Keyword List
submitter keyword: Liver, Glucose metabolism, proteomics
Contact List
Maria Nathalia Moraes
contact affiliationFederal University of Sao Paulo
contact emailmaria.nathalia@unifesp.br
lab head
Jose Thalles Lacerda
contact affiliationUniversity of Sao Paulo
contact emailthalles_lacerda2@hotmail.com
lab head
Jose Thalles Lacerda
contact affiliationUniversity of Sao Paulo
contact emailthalles_lacerda2@hotmail.com
dataset submitter
Full Dataset Link List
MassIVE dataset URI
Dataset FTP location
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