PXD031677 is an
original dataset announced via ProteomeXchange.
Dataset Summary
Title | 40S hnRNP particles are a novel class of nuclear biomolecular condensates |
Description | Heterogenous nuclear ribonucleoproteins (hnRNPs) are abundant proteins implicated in various steps of RNA processing that assemble on nuclear RNA into larger complexes termed 40S hnRNP particles. Despite their initial discovery 55 years ago, our understanding of these intriguing macromolecular assemblies remains limited. We biochemically purified native 40S hnRNP particles and determined their complete protein composition by label-free quantitative mass spectrometry, identifying A-group and C-group hnRNPs as the major protein constituents. |
HostingRepository | PRIDE |
AnnounceDate | 2022-05-30 |
AnnouncementXML | Submission_2022-05-30_01:08:01.701.xml |
DigitalObjectIdentifier | |
ReviewLevel | Peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Unsupported dataset by repository |
PrimarySubmitter | Manfred Heller |
SpeciesList | scientific name: Homo sapiens (Human); NCBI TaxID: 9606; |
ModificationList | acetylated residue; monohydroxylated residue; iodoacetamide derivatized residue; deamidated residue |
Instrument | Q Exactive HF; Q Exactive |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
0 | 2022-02-15 01:36:35 | ID requested | |
⏵ 1 | 2022-05-30 01:08:02 | announced | |
Publication List
Dataset with its publication pending |
Keyword List
submitter keyword: hnRNP, ribonucleosome, 40S particles |
Contact List
Oliver Mühlemann |
contact affiliation | University of Bern |
contact email | oliver.muehlemann@unibe.ch |
lab head | |
Manfred Heller |
contact affiliation | Proteomics and Mass Spectrometry Core Facility, Department for BioMedical Research (DBMR), University of Bern, Bern, Switzerland |
contact email | pmscf@dbmr.unibe.ch |
dataset submitter | |
Full Dataset Link List
Dataset FTP location
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PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD031677
- Label: PRIDE project
- Name: 40S hnRNP particles are a novel class of nuclear biomolecular condensates