PXD030569

PXD030569 is an original dataset announced via ProteomeXchange.

Title	Enhancer RNAs stimulate Pol II pause release by harnessing multivalent interactions to NELF
Description	UV-light-induced protein-RNA cross-linking followed by MS analysis was used to identify RNA-binding regions of enhancer RNAs (eRNAs) to the negative elongation factor (NELF) complex, and NELF as part of the paused elongation complex (PEC) of human RNA polymerase II.
HostingRepository	PRIDE
AnnounceDate	2022-03-08
AnnouncementXML	Submission_2022-03-08_07:05:43.689.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Alexander Leitner
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	iodoacetamide derivatized residue
Instrument	Orbitrap Fusion Lumos

Revision	Datetime	Status	ChangeLog Entry
0	2021-12-21 04:18:26	ID requested
⏵ 1	2022-03-08 07:05:44	announced

Dataset with its publication pending

submitter keyword: Protein-RNA complexes, protein-RNA cross-linking, UV cross-linking, RNA polymerase II, negative elongation factor (NELF), paused elongation complex (PEC)

Alexander Leitner
contact affiliation	ETH Zurich, Institute of Molecular Systems Biology, Zurich, Switzerland
contact email	leitner@imsb.biol.ethz.ch
lab head
Alexander Leitner
contact affiliation	ETH Zurich, Institute of Molecular Systems Biology
contact email	leitner@imsb.biol.ethz.ch
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2022/03/PXD030569

PRIDE project URI

• PRIDE
  1. PXD030569
     1. Label: PRIDE project
     2. Name: Enhancer RNAs stimulate Pol II pause release by harnessing multivalent interactions to NELF