PXD030206 is an
original dataset announced via ProteomeXchange.
Dataset Summary
Title | Proteomic response of SK-MEL-2 cells to polymyxin B |
Description | SK-MEL-2 cell line belongs to series of melanoma cell lines established from patient-derived tumor samples, which is usually applied in the melanin-related mechanism studies. TMT-labeling quantitative proteomics which is the state-of-art LC-MS/MS technique for protein quantitation, in this study, was applied to reveal the overall response of proteins involved in the polymyxin B-induced melanogenesis in SK-MEL-2 cells, in order to provide a possible clue at the cellular level for understanding mechanisms of polymyxin B-induced skin hyperpigmentation in clinics. |
HostingRepository | PRIDE |
AnnounceDate | 2022-03-22 |
AnnouncementXML | Submission_2022-03-22_00:32:04.051.xml |
DigitalObjectIdentifier | |
ReviewLevel | Peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Unsupported dataset by repository |
PrimarySubmitter | chuhan zhang |
SpeciesList | scientific name: Homo sapiens (Human); NCBI TaxID: 9606; |
ModificationList | iodoacetamide derivatized residue |
Instrument | Q Exactive HF |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
0 | 2021-12-06 02:55:19 | ID requested | |
⏵ 1 | 2022-03-22 00:32:04 | announced | |
Publication List
Dataset with its publication pending |
Keyword List
submitter keyword: Human, skin, melanoma cells, LC-MSMS |
Contact List
Jing Zhang |
contact affiliation | Institute of Antibiotics, Huashan Hospital, Fudan University, Shanghai, 200040, China |
contact email | 13816357098@163.com |
lab head | |
chuhan zhang |
contact affiliation | Fudan University |
contact email | 17721373354@163.com |
dataset submitter | |
Full Dataset Link List
Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2022/03/PXD030206 |
PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD030206
- Label: PRIDE project
- Name: Proteomic response of SK-MEL-2 cells to polymyxin B