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PXD030131

PXD030131 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleGlobal analysis of lysine 2-hydroxyisobutyrylation during Fusarium graminearum infection in maize
DescriptionProteins post-translational modification (PTMs) is necessary in the whole life process of organisms. Among them, lysine 2-hydroxyisobutyrylation (Khib) plays an important role in protein synthesis, transcriptional regulation, and cell metabolism. Khib is a newly identified PTM in several plant species. However, the function of Khib in maize was unclear. In this study, 2,067 Khib modified sites on 728 proteins were identified in maize. Subcellular localization results showed that these Khib modified proteins were localized in cytoplasm, chloroplast, and nucleus. We found 24 Khib sites occurred on core histones. Comparative proteomic analysis of the defense response to F. graminearum infection showed that Khib modification participated in plant resistance to pathogen infection by regulating glycolysis, TCA cycle, protein synthesis, peroxisome, and secondary metabolic processes, such as benzoxazinoid biosynthesis, phenylpropanoid biosynthesis, jasmonic acid synthesis, and tyrosine and tryptophan biosynthesis.
HostingRepositoryPRIDE
AnnounceDate2022-07-27
AnnouncementXMLSubmission_2022-07-26_18:25:57.198.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterKang Zhang
SpeciesList scientific name: Zea mays (Maize); NCBI TaxID: 4577;
ModificationListN6-(2-hydroxyisobutanoyl)-L-lysine
InstrumentQ Exactive Plus
Dataset History
RevisionDatetimeStatusChangeLog Entry
02021-12-02 07:05:48ID requested
12022-07-26 18:25:57announced
Publication List
Dataset with its publication pending
Keyword List
submitter keyword: maize
proteomic
lysine 2-hydroxyisobutyrylation
Fusarium graminearum
Contact List
Kang Zhang
contact affiliationHebei Agricultural University
contact emailzk7588@163.com
lab head
Kang Zhang
contact affiliationHebei Agricultural University
contact emailzk7588@163.com
dataset submitter
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Dataset FTP location
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