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PXD030091

PXD030091 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleThe E3 ubiquitin ligase adaptor cereblon targets the C-terminal cyclic imide degron
DescriptionWe identify cyclic imides, previously overlooked post-translation modifications, across different tissues (red blood cells and bovine lens) and human-derived cell lines and found that these modifications are globally regulated by cereblon.
HostingRepositoryPRIDE
AnnounceDate2022-07-28
AnnouncementXMLSubmission_2022-07-28_04:26:38.887.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterChristina Woo
SpeciesList scientific name: Bos taurus (Bovine); NCBI TaxID: 9913; scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationListTMT6plex-126 reporter+balance reagent acylated residue; dehydrated residue; monohydroxylated residue; iodoacetamide derivatized residue
InstrumentOrbitrap Fusion Lumos
Dataset History
RevisionDatetimeStatusChangeLog Entry
02021-12-02 02:02:23ID requested
12022-07-28 04:26:39announced
Publication List
Dataset with its publication pending
Keyword List
submitter keyword: LC-MS/MS, PTM, cyclic imide, degron, cereblon
Contact List
Christina Woo
contact affiliationDepartment of Chemistry and Chemical Biology, Harvard University
contact emailcwoo@chemistry.harvard.edu
lab head
Christina Woo
contact affiliationHarvard University
contact emailcwoo@chemistry.harvard.edu
dataset submitter
Full Dataset Link List
Dataset FTP location
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