PXD027956

PXD027956 is an original dataset announced via ProteomeXchange.

Dataset Summary

Title	Peroxynitrite in tumor microenvironment change the profile of peptide epitopes on tumor cells allowing their escape from cancer immunotherapy
Description	SILAC quantitation of MHC I peptides in mouse and human samples using LC-MS/MS. GabrilovichD-18-L005 is a representative experiment for PNT treatment of murine EG.7 with PNT and cultured afterwards for the specified amount of time (specified in the file name, in 2 replicates for 30 min time-point). GabrilovichD-17-L134 (93-2017UACC60min) is a PNT treatment of human melanoma UACC903 cells and cultured afterwards for 30 mins. GabrilovicD-20-L066 (B16mix1-HF and mix2) is an experiment with overexpression of iNOS in B16 cells (2 replicates). GabrilovichD_20-L070 is bortezomib treatment of EG7 cells for 50 min (mix1), 120 min (mix2), 300 min (mix4). Treated cells were "heavy" labeled, control cells were "light" labeled.
HostingRepository	MassIVE
AnnounceDate	2022-08-24
AnnouncementXML	Submission_2022-08-24_05:36:54.801.xml
DigitalObjectIdentifier
ReviewLevel	Non peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Hsin-Yao Tang
SpeciesList	scientific name: Homo sapiens; common name: human; NCBI TaxID: 9606; scientific name: Mus musculus; common name: house mouse; NCBI TaxID: 10090;
ModificationList	Oxidation; Carbamidomethyl
Instrument	Q Exactive HF

Dataset History

Revision	Datetime	Status	ChangeLog Entry
0	2021-08-16 09:35:27	ID requested
⏵ 1	2022-08-24 05:36:55	announced

Publication List

no publication

no publication

Keyword List

submitter keyword: Peroxynitrite, Tumor microenvironment, SILAC, MHC I peptide

submitter keyword: Peroxynitrite, Tumor microenvironment, SILAC, MHC I peptide

Contact List

Dmitry Gabrilovich
contact affiliation	AstraZeneca
contact email	dmitry.gabrilovich@astrazeneca.com
lab head
Hsin-Yao Tang
contact affiliation	The Wistar Institute
contact email	tangh@wistar.org
dataset submitter

Full Dataset Link List

MassIVE dataset URI
Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://massive.ucsd.edu/MSV000087990/

MassIVE dataset URI

Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://massive.ucsd.edu/MSV000087990/