PXD027360

PXD027360 is an original dataset announced via ProteomeXchange.

Title	Proteomic analysis of Nrf2 knocked down in HT29
Description	Colorectal cancer is known as one of the most common cancer and the third leading cause of death worldwide. Nrf2 is considered as a main transcription factor for producing antioxidants in response to oxidative stress and reduce damages to the cell. It also plays a crucial role in drug resistance. In this study, the Nrf2 gene was knocked down in HT-29 cell line and then the protein expression profile were investigated by TMT based LC MS/MS approach.
HostingRepository	PRIDE
AnnounceDate	2022-05-04
AnnouncementXML	Submission_2022-05-04_04:34:08.517.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	bahareh dabirmanesh
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	TMT6plex-126 reporter+balance reagent acylated residue
Instrument	Q Exactive

Revision	Datetime	Status	ChangeLog Entry
0	2021-07-16 03:54:48	ID requested
⏵ 1	2022-05-04 04:34:08	announced

Dataset with its publication pending

ProteomeXchange project tag: Biology/Disease-Driven Human Proteome Project (B/D-HPP), Human Proteome Project

submitter keyword: Nrf2

Reactive oxygen species

MAPK pathway

Bahareh dabirmanesh
contact affiliation	Department of Biochemistry, Faculty of Biological Science, Tarbiat Modares University, Tehran, Iran
contact email	dabirmanesh@modares.ac.ir
lab head
bahareh dabirmanesh
contact affiliation	Department of Biochemistry, Faculty of Biological Science, Tarbiat Modares University, Tehran, Iran
contact email	dabirmanesh@modares.ac.ir
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2022/05/PXD027360

PRIDE project URI

• PRIDE
  1. PXD027360
     1. Label: PRIDE project
     2. Name: Proteomic analysis of Nrf2 knocked down in HT29