PXD025742
PXD025742 is an original dataset announced via ProteomeXchange.
Dataset Summary
Title | In utero pulse-injection of isotopic amino acids quantifies protein turnover rates during murine fetal development |
Description | Protein translational control is a highly regulated step in the gene expression program during development and tools to quantify protein synthesis rates in a developing fetus are lacking. Here, we developed a novel in utero approach to quantify tissue-specific translational kinetics of the nascent proteome during mouse fetal development. The translational kinetic profiles of developing organs displayed differentially expressed protein pathways and synthesis rates which correlated with known physiological changes during mouse development. |
HostingRepository | MassIVE |
AnnounceDate | 2024-06-25 |
AnnouncementXML | Submission_2024-06-25_09:12:34.477.xml |
DigitalObjectIdentifier | |
ReviewLevel | Non peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Unsupported dataset by repository |
PrimarySubmitter | Josue Baeza |
SpeciesList | scientific name: Mus musculus; common name: house mouse; NCBI TaxID: 10090; |
ModificationList | Acetyl; Oxidation; Carbamidomethyl |
Instrument | Q Exactive; Q Exactive HF-X; Orbitrap Fusion |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
---|---|---|---|
0 | 2021-04-30 07:04:14 | ID requested | |
⏵ 1 | 2024-06-25 09:12:34 | announced |
Publication List
no publication |
Keyword List
submitter keyword: protein turnover, pSILAC, pulse-SILAC, pulse chase, development, in utero |
Contact List
Benjamin A. Garcia | |
---|---|
contact affiliation | Department of Biochemistry and Biophysics, University of Pennsylvania |
contact email | bgarci@mail.med.upenn.edu |
lab head | |
Josue Baeza | |
contact affiliation | University of Pennsylvania |
contact email | baezaj83@gmail.com |
dataset submitter |
Full Dataset Link List
MassIVE dataset URI |
Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://massive.ucsd.edu/v03/MSV000087342/ |