PXD025413

PXD025413 is an original dataset announced via ProteomeXchange.

Title	The E3 ubiquitin ligase adaptor cereblon targets the C-terminal cyclic imide degron
Description	Global quantitative proteomics of cells treated with the immunomodulatory drug pomalidomide or dipeptide degrons; global quantitative proteomics of cells treated with heterobifunctional degraders embedded with thalidomide or cyclic imide degrons; gloabl quantitative proteomics of red blood cells to search for the presence of C-terminal cyclic imide modifications on hemoglobin.
HostingRepository	PRIDE
AnnounceDate	2022-07-28
AnnouncementXML	Submission_2022-07-28_03:59:15.495.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Christina Woo
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	TMT6plex-126 reporter+balance reagent acylated residue; dehydrated residue; monohydroxylated residue; iodoacetamide derivatized residue
Instrument	Orbitrap Fusion Lumos

Revision	Datetime	Status	ChangeLog Entry
0	2021-04-15 01:42:22	ID requested
⏵ 1	2022-07-28 03:59:15	announced

Dataset with its publication pending

submitter keyword: E3, cereblon, degron, cyclic imide, IMiD

Christina Woo
contact affiliation	Department of Chemistry and Chemical Biology, Harvard University
contact email	cwoo@chemistry.harvard.edu
lab head
Christina Woo
contact affiliation	Harvard University
contact email	cwoo@chemistry.harvard.edu
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2022/07/PXD025413

PRIDE project URI

• PRIDE
  1. PXD025413
     1. Label: PRIDE project
     2. Name: The E3 ubiquitin ligase adaptor cereblon targets the C-terminal cyclic imide degron