PXD025101 is an
original dataset announced via ProteomeXchange.
Dataset Summary
Title | Contribution of IFIX to nuclear and cytoplasmic proteome changes during immune signaling |
Description | IFIX is a nuclear DNA sensor that is known to induce cytokine expression in response to both cytoplasmic DNA and foreign DNA in the nucleus. Here, we examine the concomitant nuclear and cytoplasmic proteome changes that are driven by IFIX during immune response to viral infection and transfection of viral DNA. Furthermore, we identify the posttranslational modifications present on the IFIX protein during HSV-1 infection. |
HostingRepository | PRIDE |
AnnounceDate | 2021-06-02 |
AnnouncementXML | Submission_2021-06-02_13:51:48.155.xml |
DigitalObjectIdentifier | |
ReviewLevel | Peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Unsupported dataset by repository |
PrimarySubmitter | Tim Howard |
SpeciesList | scientific name: Homo sapiens (Human); NCBI TaxID: 9606; scientific name: Human alphaherpesvirus 1; NCBI TaxID: 10298; |
ModificationList | phosphorylated residue; acetylated residue; monohydroxylated residue; iodoacetamide derivatized residue |
Instrument | Q Exactive HF; LTQ Orbitrap Velos |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
0 | 2021-03-30 03:42:44 | ID requested | |
⏵ 1 | 2021-06-02 13:51:48 | announced | |
Publication List
Dataset with its publication pending |
Keyword List
submitter keyword: Innate immunity, nuclear DNA sensor, IFIX, PTM |
Contact List
Ileana M Cristea |
contact affiliation | Department of Molecular Biology, Princeton University |
contact email | icristea@princeton.edu |
lab head | |
Tim Howard |
contact affiliation | Princeton University |
contact email | th12@princeton.edu |
dataset submitter | |
Full Dataset Link List
Dataset FTP location
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PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD025101
- Label: PRIDE project
- Name: Contribution of IFIX to nuclear and cytoplasmic proteome changes during immune signaling