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PXD024764

PXD024764 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleQuantitative proteomics of Hsp90 inhibition in Leishmania mexicana
DescriptionUsing a combination of mass spectrometry-based quantitative proteomics, chemical and metabolic labelling, we provide the first protein-level evidence that the Hsp90 inhibition affects the expression of hundreds of proteins in Leishmania spp. Our study defines the Leishmania parasite’s response to Hsp90 inhibition at its global proteome and provides a rich resource for future studies on Leishmania biology and antileishmanial drug development.
HostingRepositoryPRIDE
AnnounceDate2021-04-23
AnnouncementXMLSubmission_2021-04-23_08:49:39.731.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterKalesh Karunakaran
SpeciesList scientific name: Leishmania mexicana; NCBI TaxID: 5665;
ModificationListiodoacetamide derivatized residue
InstrumentTripleTOF 5600
Dataset History
RevisionDatetimeStatusChangeLog Entry
02021-03-16 04:57:47ID requested
12021-04-23 08:49:40announced
Publication List
Dataset with its publication pending
Keyword List
submitter keyword: Leishmania, quantitative proteomics
Contact List
Karunakaran Kalesh
contact affiliationDepartment of Chemistry, Durham University, Durham, DH1 3LE
contact emailkalesh.karunakaran@durham.ac.uk
lab head
Kalesh Karunakaran
contact affiliationDurham University
contact emailkalesh.karunakaran@durham.ac.uk
dataset submitter
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Dataset FTP location
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PRIDE project URI
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