PXD024531
PXD024531 is an original dataset announced via ProteomeXchange.
Dataset Summary
Title | Alternative polyadenylation quantitative trait loci contributing to complex trait and disease heritability |
Description | we generated nuclear and cytoplasmic extracts from FLAG-LARP4 cells, purified LARP4, using FLAG affinity resin, and analyzed the purified complexes, using mass spectrometry. Consistent with previous reports, LARP4 is primarily, but not exclusively, cytoplasmic, and we could robustly detect associated proteins involved in poly(A)-binding. Surprisingly, we also detected numerous components of the cleavage and polyadenylation machinery associated with LARP4, suggesting a potential direct role in APA regulation |
HostingRepository | MassIVE |
AnnounceDate | 2021-03-08 |
AnnouncementXML | Submission_2021-03-08_12:39:43.983.xml |
DigitalObjectIdentifier | |
ReviewLevel | Non peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Supported dataset by repository |
PrimarySubmitter | Bill Russell |
SpeciesList | scientific name: Homo sapiens; common name: human; NCBI TaxID: 9606; |
ModificationList | No PTMs are included in the dataset |
Instrument | Orbitrap Fusion ETD |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
---|---|---|---|
0 | 2021-03-04 15:59:19 | ID requested | |
⏵ 1 | 2021-03-08 12:39:44 | announced |
Publication List
no publication |
Keyword List
submitter keyword: Poly(A), APMS, LCMS |
Contact List
William Russell | |
---|---|
contact affiliation | UTMB |
contact email | bill.russell@utmb.edu |
lab head | |
Bill Russell | |
contact affiliation | UTMB |
contact email | bill.russell@utmb.edu |
dataset submitter |
Full Dataset Link List
MassIVE dataset URI |
Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://massive.ucsd.edu/MSV000087000/ |