PXD024359

PXD024359 is an original dataset announced via ProteomeXchange.

Title	Proteomic Clustering Reveals the Kinetics of Disease Biomarkers in Bovine and Human Models of Post-Traumatic Osteoarthritis
Description	Objectives: In this study, we applied a clustering method to two proteomic data sets from bovine (PRIDE PXD020756) and human models (this repository) of post-traumatic osteoarthritis (PTOA) to distinguish distinct clusters of proteins based on their kinetics of release from cartilage and examined these clusters for PTOA biomarker candidates. We quantified the effects of dexamethasone (Dex) on the kinetics of release of the cartilage media proteome.
HostingRepository	PRIDE
AnnounceDate	2023-11-14
AnnouncementXML	Submission_2023-11-14_08:52:39.813.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Patrik Onnerfjord
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	iodoacetamide derivatized residue
Instrument	Q Exactive

Revision	Datetime	Status	ChangeLog Entry
0	2021-02-24 08:06:31	ID requested
1	2021-07-22 22:57:00	announced
2	2022-03-14 08:15:24	announced	2022-03-14: Updated publication reference for DOI(s): doi.org/10.1016/j.ocarto.2021.100191.
⏵ 3	2023-11-14 08:52:40	announced	2023-11-14: Updated project metadata.

Dataset with its publication pending

submitter keyword: human cartilage, osteoarthritis, explant model

Patrik Onnerfjord
contact affiliation	Clinical Sciences, Lund University, Sweden
contact email	patrik.onnerfjord@med.lu.se
lab head
Patrik Onnerfjord
contact affiliation	Lund University
contact email	patrik.onnerfjord@med.lu.se
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2021/07/PXD024359

PRIDE project URI

• PRIDE
  1. PXD024359
     1. Label: PRIDE project
     2. Name: Proteomic Clustering Reveals the Kinetics of Disease Biomarkers in Bovine and Human Models of Post-Traumatic Osteoarthritis