PXD024060 is an
original dataset announced via ProteomeXchange.
Dataset Summary
Title | Alteration of microbiota antibody-mediated immune selection contributes to dysbiosis in IBD |
Description | The goal of this project is to find out whether human intestinal IgA1 and IgA2 secretion, transport and reactivity towards the microbiota might be involved in dysbiosis induction during Crohn’s disease and Ulcerative colitis. Mass spectrometry was used to characterize SIgA from Crohn’s disease patient and Ulcerative colitis patient, in term of O- and N-glycosylation in order to study their reverse transcytosis capacity and their role in intestinal inflammation. |
HostingRepository | PRIDE |
AnnounceDate | 2022-06-27 |
AnnouncementXML | Submission_2022-06-27_15:45:47.322.xml |
DigitalObjectIdentifier | |
ReviewLevel | Peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Unsupported dataset by repository |
PrimarySubmitter | Katell Bathany |
SpeciesList | scientific name: Homo sapiens (Human); NCBI TaxID: 9606; |
ModificationList | monohydroxylated residue; complex glycosylation; iodoacetamide derivatized residue |
Instrument | Orbitrap Fusion Lumos |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
0 | 2021-02-08 08:06:59 | ID requested | |
⏵ 1 | 2022-06-27 15:45:47 | announced | |
Publication List
Dataset with its publication pending |
Keyword List
submitter keyword: intestinal disease, immune mucosal response, IgA modifications, glycosylations |
Contact List
Caroline TOKARSKI |
contact affiliation | CBMN UMR5248 CNRS-Univ. Bordeaux |
contact email | c.tokarski@cbmn.u-bordeaux.fr |
lab head | |
Katell Bathany |
contact affiliation | University of Bordeaux |
contact email | k.bathany@cbmn.u-bordeaux.fr |
dataset submitter | |
Full Dataset Link List
Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2022/06/PXD024060 |
PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD024060
- Label: PRIDE project
- Name: Alteration of microbiota antibody-mediated immune selection contributes to dysbiosis in IBD