PXD023764
PXD023764 is an original dataset announced via ProteomeXchange.
Dataset Summary
| Title | Multi-platform omics analysis of Nipah virus infection reveals viral glycoprotein modulation of mitochondria: proteomics |
| Description | We analyzed changes in cellular components and processes during NiV infection through a time-course exposure using live virus and individual genes (or combinations) via transfection. Our multi-omics approach has displayed an enrichment in mitochondrial proteins. This enrichment phenotype was also observed when we combine viral glycoprotein genes in transfection experiments. These analyses provide an atlas of cellular changes during NiV infections, helpful in designing therapeutics against rapidly growing Henipavirus genes and related infections. |
| HostingRepository | MassIVE |
| AnnounceDate | 2025-03-25 |
| AnnouncementXML | Submission_2025-03-25_09:20:11.697.xml |
| DigitalObjectIdentifier | |
| ReviewLevel | Non peer-reviewed dataset |
| DatasetOrigin | Original dataset |
| RepositorySupport | Supported dataset by repository |
| PrimarySubmitter | Matthew Monroe |
| SpeciesList | scientific name: Homo sapiens; common name: human; NCBI TaxID: 9606; |
| ModificationList | Oxidation; Carbamidomethyl; Phospho; TMT6plex |
| Instrument | Q Exactive; Q Exactive HF |
Dataset History
| Revision | Datetime | Status | ChangeLog Entry |
|---|---|---|---|
| 0 | 2021-01-23 01:31:34 | ID requested | |
| ⏵ 1 | 2025-03-25 09:20:12 | announced |
Publication List
| no publication |
Keyword List
| submitter keyword: Nipah virus, paramyxovirus, transcriptomics, proteomics, infection |
Contact List
| Joshua N. Adkins | |
|---|---|
| contact affiliation | Pacific Northwest National Laboratory |
| contact email | Joshua.Adkins@pnnl.gov |
| lab head | |
| Hector Aguilar-Carreno | |
| contact affiliation | Department of Microbiology and Immunology, Cornell University |
| contact email | ha363@cornell.edu |
| lab head | |
| Matthew Monroe | |
| contact affiliation | Pacific Northwest National Laboratory |
| contact email | matthew.monroe@pnnl.gov |
| dataset submitter | |
Full Dataset Link List
| MassIVE dataset URI |
| Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://massive.ucsd.edu/v03/MSV000086754/ |
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