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PXD023530

PXD023530 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleProteomic characterization of bacteriophage peptides from mastitis producer Staphylococcus aureus by LC-ESI-MS/MS and their bacteriophage phylogenomic analysis
DescriptionThe present work describes LC-ESI-MS/MS analyses of tryptic digestion peptides from phages that infect Staphylococcus aureus-causing mastitis, and isolated from dairy products. A total of 1935 non-redundant peptides belonging to 1282 proteins were identified and analyzed. Among them, 80 staphylococcal peptides from phages were confirmed. These peptides belong to proteins such as phage repressors, structural phage proteins, uncharacterized phage proteins and complement inhibitors. Moreover, of the phage origin peptides found, eighteen of them were specific to S. aureus strains. These diagnostic peptides could be useful for the identification and characterization of S. aureus strains that cause mastitis. Furthermore, a study of bacteriophage phylogeny and the relationship among the identified phage peptides and the bacteria they infect was also performed. The results show the specific peptides which are present in closely related phages, and the existing links between bacteriophage phylogeny and the respective Staphylococcus spp. infected.
HostingRepositoryPRIDE
AnnounceDate2021-03-25
AnnouncementXMLSubmission_2021-03-25_11:25:49.624.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterMónica Carrera
SpeciesList scientific name: Staphylococcus aureus; NCBI TaxID: 1280;
ModificationListacetylated residue; monohydroxylated residue; iodoacetamide derivatized residue
InstrumentLTQ Orbitrap
Dataset History
RevisionDatetimeStatusChangeLog Entry
02021-01-11 10:43:33ID requested
12021-03-25 11:25:50announced
Publication List
Dataset with its publication pending
Keyword List
submitter keyword: pathogen detection
LC-ESI-MS/MS
proteomics
mass spectrometry
phage peptide biomarker
Contact List
Mónica Carrera
contact affiliationCSIC
contact emailmcarrera@iim.csic.es
lab head
Mónica Carrera
contact affiliationCSIC
contact emailmcarrera@iim.csic.es
dataset submitter
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Dataset FTP location
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