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PXD022149

PXD022149 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleCeragenins and antimicrobial peptides kill bacteria through distinct mechanisms
DescriptionCeragenins are a family of synthetic amphipathic molecules designed to mimic the properties of naturally-occurring cationic antimicrobial peptides (CAMPs). Although ceragenins have potent antimicrobial activity, whether their mode of action is similar to that of CAMPs has remained elusive. Here we report the results of a comparative study of the bacterial responses to two well-studied CAMPs, LL37 and colistin, and two ceragenins with related structures, CSA13 and CSA13.
HostingRepositoryPRIDE
AnnounceDate2022-01-10
AnnouncementXMLSubmission_2022-01-10_10:45:36.906.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterJonathan Budzik
SpeciesList scientific name: Escherichia coli; NCBI TaxID: 562;
ModificationListNo PTMs are included in the dataset
InstrumentOrbitrap Fusion Lumos
Dataset History
RevisionDatetimeStatusChangeLog Entry
02020-10-23 01:25:35ID requested
12022-01-10 10:45:37announced
Publication List
Dataset with its publication pending
Keyword List
submitter keyword: Antibiotics, Gram-negative, Gram-positive, mycobacteria, CSA
Contact List
Jeffery S Coox
contact affiliationMolecular and Cell Biology University of California, Berkeley
contact emailjeff.cox@berkeley.edu
lab head
Jonathan Budzik
contact affiliationUCSF
contact emailjonathan.budzik2@ucsf.edu
dataset submitter
Full Dataset Link List
Dataset FTP location
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PRIDE project URI
Repository Record List
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