PXD021905

PXD021905 is an original dataset announced via ProteomeXchange.

Dataset Summary

Title	Respiratory vinyl chloride reductive dechlorination to ethene in TceA-expressing Dehalococcoides mccartyi
Description	Organohalide-respiring Dehalococcoidia bacteria are one of the few microorganisms capable of transforming chlorinated solvents to benign ethene in anoxic environments. The tceA gene found in these bacteria, coding the trichloroethene-dechlorinating RDase TceA, is frequently detected in contaminated groundwater but not recognized as a biomarker for vinyl chloride detoxification. Here, we demonstrate that the tceA-carrying Dehalococcoides mccartyi (Dhc) strains FL2 and 195 grow with VC as electron acceptor when sufficient vitamin B12 is provided. Global proteomic profiling confirmed the predominant TceA expression in VC-grown Dhc FL2 cells, providing a line of evidence for the implication of TceA in respiratory VC reductive dechlorination.
HostingRepository	MassIVE
AnnounceDate	2020-10-12
AnnouncementXML	Submission_2020-10-12_07:10:29.xml
DigitalObjectIdentifier
ReviewLevel	Non peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Manuel Villalobos Solis
SpeciesList	scientific name: Dehalococcoides mccartyi; NCBI TaxID: 61435;
ModificationList	Oxidation
Instrument	LTQ XL

Dataset History

Revision	Datetime	Status	ChangeLog Entry
0	2020-10-09 09:18:59	ID requested
⏵ 1	2020-10-12 07:10:29	announced

Publication List

no publication

no publication

Keyword List

submitter keyword: Dehalococcoides, strain FL2, vinyl chloride, TceA

submitter keyword: Dehalococcoides, strain FL2, vinyl chloride, TceA

Contact List

Frank E. Loffler
contact affiliation	University of Tennessee-Knoxville
contact email	frank.loeffler@utk.edu
lab head
Manuel Villalobos Solis
contact affiliation	University of Tennessee/Oak Ridge National Laboratory
contact email	mvillal1@vols.utk.edu
dataset submitter

Full Dataset Link List

MassIVE dataset URI
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MassIVE dataset URI

Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://massive.ucsd.edu/MSV000086254/