PXD021378

PXD021378 is an original dataset announced via ProteomeXchange.

Dataset Summary

Title	A Landscape of Ectodomain Shedding by Quantitative Protein Terminomics
Description	Ectodomain shedding is a proteolytic process that regulates level and function of membrane proteins. By quantitative protein terminomics consisting of N- and C-terminal peptide enrichment, TMT-labeling and mass spectrometry, we quantified protein termini in the cultured media across 10 human cell lines and identified cleavage sites on membrane proteins downregulated upon broad-spectrum metalloprotease inhibitor treatment.
HostingRepository	jPOST
AnnounceDate	2021-03-05
AnnouncementXML	Submission_2022-09-18_03:34:18.800.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Kazuya Tsumagari
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	S-carboxamidomethyl-L-cysteine; alpha-amino acetylated residue; L-methionine sulfoxide
Instrument	instrument

Dataset History

Revision	Datetime	Status	ChangeLog Entry
0	2020-09-09 07:19:51	ID requested
1	2021-03-04 16:38:24	announced
2	2021-04-03 09:17:08	announced	2021-04-04: Updated PubMed.
⏵ 3	2022-09-18 03:34:19	announced	2022-09-18: Updated FTP location.

Keyword List

submitter keyword: ectodomain shedding, cleavage site, protein terminomics, metalloprotease, membrane protein, proteomics, mass spectrometry, secretome, proteolysis, degradomics

submitter keyword: ectodomain shedding, cleavage site, protein terminomics, metalloprotease, membrane protein, proteomics, mass spectrometry, secretome, proteolysis, degradomics

Contact List

Yasushi Ishihama
lab head
Kazuya Tsumagari
contact affiliation	Keio University
dataset submitter

Full Dataset Link List

jPOST dataset URI
Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.jpostdb.org/JPST000632/

jPOST dataset URI

Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.jpostdb.org/JPST000632/