PXD021160

PXD021160 is an original dataset announced via ProteomeXchange.

Title	Proteomics of Rat Proximal-Tubule Cell-Culture Models
Description	Cultured cell lines are widely used for research in the physiology, pathophysiology, toxicology and pharmacology of the renal proximal tubule. The lines that are most appropriate for a given use depend on the genes expressed. New tools for transcriptomic and proteomic profiling using RNA-sequencing (RNA-Seq) and mass spectrometry make it possible to catalog expressed genes in each cell line. This data set is the protoemic data of Rat NRK-52E cell line. We concludeno cell line fully matched the transcriptome of native proximal tubule cells. However, some of the lines tested are suitable for the study of particular metabolic and transport processes seen in the proximal tubule.
HostingRepository	PRIDE
AnnounceDate	2020-10-15
AnnouncementXML	Submission_2020-10-14_23:20:01.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	CHIN-RANG YANG
SpeciesList	scientific name: Rattus norvegicus (Rat); NCBI TaxID: 10116;
ModificationList	TMT6plex-126 reporter+balance reagent acylated residue; monohydroxylated residue; iodoacetamide derivatized residue
Instrument	Orbitrap Fusion Lumos

Revision	Datetime	Status	ChangeLog Entry
0	2020-08-27 01:47:01	ID requested
⏵ 1	2020-10-14 23:20:02	announced

Dataset with its publication pending

submitter keyword: Rat, Kideny, Proximal Tubule

Mark A. Knepper
contact affiliation	Principal Investigator Epithelial Systems Biology Laboratory Systems Biology Center Division of Intramural Research National Heart, Lung and Blood Institute 10 CENTER DR MSC-1603 Building 10, Room 6N307 Bethesda Maryland 20892-1603
contact email	knepperm@nhlbi.nih.gov
lab head
CHIN-RANG YANG
contact affiliation	National Institutes of Health, USA
contact email	chin-rang.yang@nih.gov
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2020/10/PXD021160

PRIDE project URI

• PRIDE
  1. PXD021160
     1. Label: PRIDE project
     2. Name: Proteomics of Rat Proximal-Tubule Cell-Culture Models