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PXD021076

PXD021076 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleProteomics profiling of pediatric choroid plexus tumors
DescriptionAggresome is a para nuclear inclusion body that functions as a storage compartment for misfolded proteins. Our previous work revealed the presence of aggresomes in pediatric choroid plexus tumors (CPT). CPTs are rare neoplasms comprised of three pathological subgroups; choroid plexus carcinoma (CPC), a grade III tumor, atypical choroid plexus papilloma (ACPP), a grade II tumor, and choroid plexus papilloma (CPP), a grade I tumor. In the current study, we aimed to investigate the prognostic value of aggresomes-positivity and its correlation to the pathological and molecular subtypes. The proteomics profiling of 21 CPT pediatric samples was investigated using ABSciex Triple TOF 5600+ mass spectrometer.
HostingRepositoryPRIDE
AnnounceDate2021-02-11
AnnouncementXMLSubmission_2021-02-11_01:05:49.xml
DigitalObjectIdentifierhttps://dx.doi.org/10.6019/PXD021076
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportSupported dataset by repository
PrimarySubmitterNouran Al-Shehaby
SpeciesList scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationListacetylated residue; monohydroxylated residue; iodoacetamide derivatized residue; deamidated residue
InstrumentTripleTOF 5600
Dataset History
RevisionDatetimeStatusChangeLog Entry
02020-08-24 02:38:47ID requested
12021-02-11 01:05:49announced
Publication List
Dataset with its publication pending
Keyword List
ProteomeXchange project tag: Biology/Disease-Driven Human Proteome Project (B/D-HPP), Human Proteome Project
submitter keyword: Human, Pediatric, Cancer, Tumor, Choroid Plexus, Tissue, Pappiloma, Atypical, Carcinoma
Contact List
Shahenda Mahmoud El-Naggar
contact affiliationTumor Biology Research Program, Basic Research Unit, Research Department, Children's Cancer Hospital Egypt 57357
contact emailshahenda.elnaggar@57357.org
lab head
Nouran Al-Shehaby
contact affiliationChildren's Cancer Hospital Egypt 57357
contact emailnouran.alshehaby@57357.org
dataset submitter
Full Dataset Link List
Dataset FTP location
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