PXD020954 is an
original dataset announced via ProteomeXchange.
Dataset Summary
Title | Chicken microbiome LC - MS / MS |
Description | Bacteroidaceae are common gut microbiota members in all warm-blooded animals. However, if Bacteroidaceae are to be used as probiotics, the species selected for different hosts should reflect the natural distribution. In this study, we therefore evaluated host adaptation of bacterial species belonging to the family Bacteroidaceae. B. dorei, B. uniformis, B. xylanisolvens, B. ovatus, B. clarus, B. thetaiotaomicron and B. vulgatus represented human-adapted species while B. gallinaceum, B. caecigallinarum, B. mediterraneensis, B. caecicola, M. massiliensis, B. plebeius and B. coprocola were commonly detected in chicken but not human gut microbiota. There were 29 genes which were present in all human-adapted Bacteroides but absent from the genomes of all chicken isolates and these included genes required for the pentose cycle, and glutamate or histidine metabolism. These genes were expressed during an in vitro competitive assay, in which human-adapted Bacteroides species overgrew the chicken adapted isolates. Not a single gene specific for the chicken-adapted species was found. Instead, chicken adapted species exhibited signs of frequent horizontal gene transfer, of KUP, linA and sugE genes in particular. The differences in host adaptation should be considered when the new generation of probiotics for humans or chickens is designed. |
HostingRepository | PRIDE |
AnnounceDate | 2020-09-28 |
AnnouncementXML | Submission_2020-09-27_23:58:25.xml |
DigitalObjectIdentifier | |
ReviewLevel | Peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Unsupported dataset by repository |
PrimarySubmitter | Zuzana Seidlerova |
SpeciesList | scientific name: Bacteroides sp. 1_1_11; NCBI TaxID: 469584; |
ModificationList | monohydroxylated residue; iodoacetamide derivatized residue |
Instrument | LTQ Velos |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
0 | 2020-08-17 03:35:53 | ID requested | |
⏵ 1 | 2020-09-27 23:58:25 | announced | |
Publication List
Dataset with its publication pending |
Keyword List
submitter keyword: Microbiota, Microbiome, Chicken, Caecum, Bacteroides |
Contact List
doc. RNDr. RYCHLĂK Ivan, Ph.D. |
contact affiliation | Veterinary Research Institute Department:MICROBIOLOGY AND ANTIMICROBIAL RESISTANCE Hudcova 296/70 621 00 Brno Czech Republic |
contact email | rychlik@vri.cz |
lab head | |
Zuzana Seidlerova |
contact affiliation | Veterinary Research Institute Hudcova 296/70 621 00 Brno Czech Republic |
contact email | seidlerova@vri.cz |
dataset submitter | |
Full Dataset Link List
Dataset FTP location
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PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD020954
- Label: PRIDE project
- Name: Chicken microbiome LC - MS / MS