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PXD020378

PXD020378 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitlePhenotypical adaptation of Pseudomonas aeruginosa in the presence of siderophore-antibiotic conjugates during epithelial cell infection
DescriptionThis study aims at investigating the ability of Pseudomonas aeruginosa to detect the presence of siderophore-antibiotic conjugates in an epithelial cell infection assay. We show that the presence of siderophore-antibiotic conjugates induces the transcription and expression of their corresponding transporters, indicating the bacteria are able to sense the chelators in their environment and adapt their phenotype accordingly.
HostingRepositoryPRIDE
AnnounceDate2024-10-22
AnnouncementXMLSubmission_2024-10-22_05:19:07.032.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterPaola Cantero
SpeciesList scientific name: Homo sapiens (Human); NCBI TaxID: 9606; scientific name: Pseudomonas aeruginosa PAO1; NCBI TaxID: 208964;
ModificationListmonohydroxylated residue; iodoacetamide derivatized residue
InstrumentQ Exactive Plus
Dataset History
RevisionDatetimeStatusChangeLog Entry
02020-07-15 06:55:49ID requested
12021-02-18 05:59:30announced
22024-10-22 05:19:07announced2024-10-22: Updated project metadata.
Publication List
Dataset with its publication pending
Keyword List
submitter keyword: sideromycin, Trojan Horse antibiotic,Pseudomonas aeruginosa, siderophore, nanoLC-MS/MS, label-free analysis.
Contact List
Laurence Sabatier
contact affiliationIPHC (LSMBO-Laboratoire de Spectrométrie de Masse Bio-Organique), UMR 7178, Université de Strasbourg, CNRS
contact emaillaurence.sabatier@unistra.fr
lab head
Paola Cantero
contact affiliationIPHC (LSMBO-Laboratoire de Spectrométrie de Masse Bio-Organique), UMR 7178, Université de Strasbourg, CNRS
contact emailliz-paola.cantero-mendieta@etu.unistra.fr
dataset submitter
Full Dataset Link List
Dataset FTP location
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PRIDE project URI
Repository Record List
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