PXD018682 is an
original dataset announced via ProteomeXchange.
Dataset Summary
Title | MS analysis of SARS-CoV2 proteins from patient samples |
Description | We developed a simple, MS-based method to specifically detect SARS-CoV-2 proteins from gargle solution samples of COVID-19 patients. Our protocol consists of an acetone precipitation and tryptic digestion of proteins contained within the gargle solution, followed by a targeted MS analysis. Our methodology identifies unique peptides originating from SARS-CoV-2 nucleoprotein. Building on these promising initial results, faster MS protocols can now be developed as routine diagnostic tools for COVID-19 patients. https://biorxiv.org/cgi/content/short/2020.04.18.047878v1 |
HostingRepository | PRIDE |
AnnounceDate | 2020-04-24 |
AnnouncementXML | Submission_2020-04-24_03:52:36.xml |
DigitalObjectIdentifier | https://dx.doi.org/10.6019/PXD018682 |
ReviewLevel | Peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Supported dataset by repository |
PrimarySubmitter | Christian Ihling |
SpeciesList | scientific name: Homo sapiens (Human); NCBI TaxID: 9606; |
ModificationList | Met-loss; Deamidated; Met-loss+Acetyl; Oxidation; Acetyl; Carbamidomethyl; iodoacetamide derivatized residue |
Instrument | Orbitrap Fusion |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
0 | 2020-04-20 08:41:12 | ID requested | |
⏵ 1 | 2020-04-24 03:52:37 | announced | |
Publication List
Dataset with its publication pending |
Keyword List
ProteomeXchange project tag: Biology/Disease-Driven Human Proteome Project (B/D-HPP), Human Proteome Project |
submitter keyword: COVID-19, Mass spectrometry, Nucleoprotein, SARS-CoV-2 |
Contact List
Andrea Sinz |
contact affiliation | Martin-Luther University Halle-Wittenberg Institute of Pharmacy Department of Pharmaceutical Chemistry & Bioanalytics Charles Tanford Protein Center |
contact email | andrea.sinz@pharmazie.uni-halle.de |
lab head | |
Christian Ihling |
contact affiliation | MLU Halle, Inst. f. Pharmacy |
contact email | christian.ihling@pharmazie.uni-halle.de |
dataset submitter | |
Full Dataset Link List
Dataset FTP location
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PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD018682
- Label: PRIDE project
- Name: MS analysis of SARS-CoV2 proteins from patient samples