PXD016976
PXD016976 is an original dataset announced via ProteomeXchange.
Dataset Summary
Title | Mass Spectrometry-GUided Immunoassay DEvelopment (MS-GUIDE) |
Description | We applied targeted MS (parallel reaction monitoring, PRM) to pre-qualify candidates for clinical ELISA assay development. Literature harvested potential biomarker candidates, for which typically no antibodies for sensitive detection in complex samples exist, were evaluated in a medium-sized patient cohort using PRM. After biomarker validation, clinical grade ELISAs were developed and tested in a larger independent patient cohort. |
HostingRepository | PanoramaPublic |
AnnounceDate | 2022-04-14 |
AnnouncementXML | Submission_2022-04-14_19:20:21.319.xml |
DigitalObjectIdentifier | |
ReviewLevel | Non peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | supported by repository but incomplete data and/or metadata |
PrimarySubmitter | Sandra Goetze |
SpeciesList | scientific name: Homo sapiens; NCBI TaxID: 9606; |
ModificationList | Deamidated; Carbamidomethyl; Oxidation; Label:13C(6)15N(4); Label:13C(6)15N(2) |
Instrument | Orbitrap Fusion ETD; Q Exactive Plus |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
---|---|---|---|
0 | 2020-01-06 22:23:44 | ID requested | |
⏵ 1 | 2022-04-14 19:20:21 | announced |
Publication List
Dataset with its publication pending |
Keyword List
submitter keyword: prostate cancer, serum, glycocapture, biomarker, ELISA, PRM |
Contact List
Bernd Wollscheid | |
---|---|
contact affiliation | ETHZ |
contact email | bernd.wollscheid@hest.ethz.ch |
lab head | |
Sandra Goetze | |
contact affiliation | ETHZ |
contact email | sgoetze@ethz.ch |
dataset submitter |
Full Dataset Link List
Panorama Public dataset URI |