PXD016608
PXD016608 is an original dataset announced via ProteomeXchange.
Dataset Summary
Title | The Q61H mutation decouples KRAS from upstream regulation and renders cancer cells resistant to SHP2 inhibitors |
Description | Data contains results of LC-MS/MS analysis of KRAS4B-Q61H tyrosine phosphorylation following in vitro kinase reaction with Src kinase. Protein was denatured, reduced and alkylated and digested with Trypsin/Lys-C. |
HostingRepository | MassIVE |
AnnounceDate | 2021-08-20 |
AnnouncementXML | Submission_2021-08-20_05:29:56.125.xml |
DigitalObjectIdentifier | |
ReviewLevel | Non peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Supported dataset by repository |
PrimarySubmitter | Jonathan St-Germain |
SpeciesList | scientific name: Homo sapiens; common name: human; NCBI TaxID: 9606; |
ModificationList | Deamidated; Acetyl; Oxidation; Carbamidomethyl; Phospho |
Instrument | instrument model |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
---|---|---|---|
0 | 2019-12-04 08:16:36 | ID requested | |
⏵ 1 | 2021-08-20 05:29:56 | announced |
Publication List
no publication |
Keyword List
submitter keyword: KRAS, LC-MS, tyorsine, phosphorylation, in vitro, kinase assay |
Contact List
Brian Raught | |
---|---|
contact affiliation | Princess Margaret Cancer Centre |
contact email | brian.raught@gmail.com |
lab head | |
Jonathan St-Germain | |
contact affiliation | Princess Margaret Cancer Centre |
contact email | jonstgermain@gmail.com |
dataset submitter |
Full Dataset Link List
MassIVE dataset URI |
Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://massive.ucsd.edu/MSV000084657/ |